Effect of acute alcohol intoxication on the opioid system in humans.
Alcohol
; 12(6): 559-62, 1995.
Article
en En
| MEDLINE
| ID: mdl-8590619
We investigated the possible relations between the endogenous opioid system and acute alcoholic intoxication in 21 subjects, of whom 13 were drinkers who came to the emergency service with evident symptoms of drunkenness, and 8 were nondrinkers who consumed 1 g alcohol per kg body weight over a short period. Different patterns of changes were found in the two groups for plasma concentrations of beta-endorphin and adrenocorticotropic hormone. In drinkers, plasma levels of both substances increased, whereas in nondrinkers both concentrations decreased, the declines being especially notable 15, 30, and 45 min after ingestion. We found no differences between the two groups in plasma cortisol concentrations. The different levels of these substances may reflect differences in drinking behavior between the two groups.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Hidrocortisona
/
Betaendorfina
/
Hormona Adrenocorticotrópica
/
Intoxicación Alcohólica
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Alcohol
Asunto de la revista:
TRANSTORNOS RELACIONADOS COM SUBSTANCIAS
Año:
1995
Tipo del documento:
Article
País de afiliación:
España
Pais de publicación:
Estados Unidos