Interplay between mycoplasmas and host target cells.

Baseman, J B; Lange, M; Criscimagna, N L; Giron, J A; Thomas, C A

Baseman, J B; Lange, M; Criscimagna, N L; Giron, J A; Thomas, C A.

Afiliación

Baseman JB; Department of Microbiology, University of Texas Health Science Center at San Antonio 78284-7758, USA.

Microb Pathog ; 19(2): 105-16, 1995 Aug.

Article en En | MEDLINE | ID: mdl-8577234

RESUMEN

The infectious pattern of mycoplasmas (Mycoplasma penetrans, Mycoplasma pneumoniae and Mycoplasma genitalium) in mammalian cells was examined using confocal microscopy and flow cytometry combined with cell fractionation and mycoplasma viability determinations. Within 2 h postinfection mycoplasmas parasitize cell surfaces, enter the intracellular spaces and locate throughout the cytoplasmic and perinuclear regions. These mycoplasmas can be cultivated from cytoplasmic and nuclear fractions 96 h later and continue to persist intracellularly for at least 7 days, suggesting a much more active intracellular role for mycoplasmas than had been considered previously.

Asunto(s)

Pulmón/microbiología; Mycoplasma penetrans/fisiología; Mycoplasma pneumoniae/fisiología; Animales; Fraccionamiento Celular; Línea Celular; Citometría de Flujo/métodos; Humanos; Pulmón/citología; Microscopía Confocal; Mycoplasma penetrans/crecimiento & desarrollo; Mycoplasma pneumoniae/crecimiento & desarrollo

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Mycoplasma penetrans / Pulmón / Mycoplasma pneumoniae Límite: Animals / Humans Idioma: En Revista: Microb Pathog Asunto de la revista: DOENCAS TRANSMISSIVEIS / MICROBIOLOGIA Año: 1995 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

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