Reliability of fine needle aspiration cytology for distinguishing between carcinoma, lymphoma and sarcoma; the influence of clinical information.
Cytopathology
; 4(2): 107-14, 1993.
Article
en En
| MEDLINE
| ID: mdl-8485309
To investigate interobserver variation of fine needle aspiration (FNA) cytological diagnosis with respect to distinguishing between carcinoma, sarcoma and lymphoma, a set of 80 randomly sampled slides was randomized twice and read 'blindly' by five cytopathologists. In the first round the slides were read without any information, and in the second round clinical information was provided. Histology was used as a reference standard. In the first round, the positive predictive values for the cytological diagnosis of carcinoma, sarcoma and lymphoma were 93%, 94% and 86% respectively. In the second round the positive predictive values for the cytological diagnoses of carcinoma, sarcoma and lymphoma were 95%, 99% and 99%, respectively. Interobserver variability, tested with weighted kappa scores (range 0.73-0.92) between histological and cytological diagnosis, was low. The most accurate FNA cytologic classification was obtained when the clinical context was known.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Sarcoma
/
Biopsia con Aguja
/
Carcinoma
/
Linfoma
Tipo de estudio:
Clinical_trials
/
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Cytopathology
Asunto de la revista:
PATOLOGIA
Año:
1993
Tipo del documento:
Article
País de afiliación:
Países Bajos
Pais de publicación:
Reino Unido