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Characterization of kinetoplast DNA from Phytomonas serpens.
Sá-Carvalho, D; Perez-Morga, D; Traub-Cseko, Y M.
Afiliación
  • Sá-Carvalho D; Departamento de Bioquímica e Biologia Molecular, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
J Eukaryot Microbiol ; 40(3): 317-22, 1993.
Article en En | MEDLINE | ID: mdl-8389640
The restriction enzyme digestion of kinetoplast DNA from four Phytomonas serpens isolates shows an overall similar band pattern. One minicircle from isolate 30T was cloned and sequenced, showing low levels of homology but the same general features and organization as described for minicircles of other trypanosomatids. Extensive regions of the minicircle are composed by G and T on the H strand. These regions are very repetitive and similar to regions in a minicircle of Crithidia oncopelti and to telomeric sequences of Saccharomyces cerevisiae. Conserved Sequence Block 3, present in all trypanosomatids, is one nucleotide different from the consensus in P. serpens and provides a basis to differentiate P. serpens from other trypanosomatids. Electron microscopy of kinetoplast DNA evidenced a network with organization similar to other trypanosomatids and the measurement of minicircles confirmed the size of about 1.45 kb of the sequenced minicircle.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ADN Circular / ADN Protozoario / Trypanosomatina Límite: Animals Idioma: En Revista: J Eukaryot Microbiol Asunto de la revista: MICROBIOLOGIA / PARASITOLOGIA Año: 1993 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ADN Circular / ADN Protozoario / Trypanosomatina Límite: Animals Idioma: En Revista: J Eukaryot Microbiol Asunto de la revista: MICROBIOLOGIA / PARASITOLOGIA Año: 1993 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos