Efficacy of monoclonal antibodies against adhesion molecules in animal models of asthma.
Agents Actions Suppl
; 43: 151-62, 1993.
Article
en En
| MEDLINE
| ID: mdl-8368159
Cell surface adhesive glycoproteins are principal regulators of nearly all aspects of immune/inflammatory responses. Using monoclonal antibodies to individual adhesion molecules, the expression and contribution of specific molecules in the pathogenesis of allergen-induced airway hyperresponsiveness in monkeys has been deciphered. Results confirm the importance of cell adhesion and demonstrate that antagonism of a single adhesion molecule may provide a novel therapeutic approach.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Asma
/
Moléculas de Adhesión Celular
/
Anticuerpos Monoclonales
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Agents Actions Suppl
Año:
1993
Tipo del documento:
Article
Pais de publicación:
Suiza