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Treatment of active distal ulcerative colitis with immunoglobulin G enemas.
Jarløv, A E; Munkholm, P; Schmidt, P N; Langholz, E; Vestergaard, B F; Bech, R M.
Afiliación
  • Jarløv AE; Department of Medical Gastroenterology C, Herlev Hospital, University of Copenhagen, Denmark.
Aliment Pharmacol Ther ; 7(5): 561-5, 1993 Oct.
Article en En | MEDLINE | ID: mdl-8280825
Seven patients with active distal ulcerative colitis were treated with IgG enemas given as a daily bedtime retention enema for two weeks. Evaluation of effect was assessed by means of sigmoidoscopy with biopsy, measuring acute phase reactants in peripheral blood, and measuring the faecal protein loss. Clinical signs of active disease were registered by the patients on a diary chart. Five patients completed the treatment period, two patients were withdrawn after 7 and 10 days due to deterioration of disease. Four patients did not register any effect, whereas one patient improved clinically. In conclusion, rectally administered IgG did not exert any effect on rectal ulcerative colitis in our study.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoglobulina G / Colitis Ulcerosa Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Aliment Pharmacol Ther Asunto de la revista: FARMACOLOGIA / GASTROENTEROLOGIA / TERAPIA POR MEDICAMENTOS Año: 1993 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoglobulina G / Colitis Ulcerosa Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Aliment Pharmacol Ther Asunto de la revista: FARMACOLOGIA / GASTROENTEROLOGIA / TERAPIA POR MEDICAMENTOS Año: 1993 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Reino Unido