[Lipid adjustment of alpha-tocopherol concentrations in plasma]. / Lipid-Adjustierung von alpha-Tocopherolkonzentrationen im Plasma.
Z Ernahrungswiss
; 32(3): 219-28, 1993 Sep.
Article
en De
| MEDLINE
| ID: mdl-8237081
Measurement of alpha-tocopherol concentrations circulating either in plasma or serum is the most common method of measuring the vitamin E status in men. The analytical determination with a suitable HPLC method produces precise and reliable results. The interpretation of the measured alpha-tocopherol values is complicated by the strong positive correlation with different blood lipids. A considerable misinterpretation of the data will occur if these confounding factors are not taken into account by a suitable adjustment. Different methods have been described in the literature which tried to control the confounding effect of blood lipids. These methods were not completely satisfying. Therefore, a mathematical regression model, based on residuals, is introduced and applied to the data of the VERA-study (Verbundstudie Ernährungserhebung und Risikofaktoren Analytik) and the consequences of the lipid-adjustment of the tocopherol values are studied in further statistical procedures. Thereafter, lipid-adjusted tocopherol concentrations can be subjected to more extensive statistical evaluations without the requirement of special stratification.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Vitamina E
/
Lípidos
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
De
Revista:
Z Ernahrungswiss
Año:
1993
Tipo del documento:
Article
Pais de publicación:
Alemania