[Cytogenetic study of fragmented embryos not transferred in in vitro fertilization]. / Etude cytogénétique des embryons fragmentés et non transférés en fécondation in vitro.
Ann Genet
; 36(2): 94-9, 1993.
Article
en Fr
| MEDLINE
| ID: mdl-8215225
A cytogenetic analysis was performed on a sample of 411 human grade IV embryos (i.e. poor morphological quality embryos, never transferred in our in vitro fertilization (IVF) pro Gram) in order to investigate the chromosomal status of these embryos. One hundred eighteen were successfully karyotyped from at least one metaphase. Only 10% displayed normal diploid metaphases. Aneuploidy was the most frequently observed abnormality, with a rate of 36.4%. Six cases of single chromatids were noted and 9 embryos showed structural aberrations. Polyploidy (from 3n to 7n) and haploidy were also observed, suggesting parthenogenetic activation, polyspermy or chromosomal duplication. Mosaicism constituted 6% of the abnormalities. Thirty embryos exhibited fragmented chromosome sets which might result from in vitro delayed fertilization.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Fertilización In Vitro
/
Aberraciones Cromosómicas
/
Embrión de Mamíferos
Límite:
Humans
Idioma:
Fr
Revista:
Ann Genet
Año:
1993
Tipo del documento:
Article
Pais de publicación:
Países Bajos