[Platelet function after allogeneic bone marrow transplantation in Wiskott-Aldrich syndrome]. / Estudio de la función plaquetaria después del trasplante alogénico de medula ósea en el síndrome de Wiskott-Aldrich.
Sangre (Barc)
; 38(3): 233-4, 1993 Jun.
Article
en Es
| MEDLINE
| ID: mdl-8211550
PURPOSE: To assess the platelet characteristics and functionalism in the Wiskott-Aldrich syndrome (WAS) after allogeneic BMT using cyclophosphamide and busulphan for conditioning. MATERIAL AND METHODS: Two WAS patients underwent allogeneic BMT. Platelet aggregation was studied prior to and after BMT, along with the intraplatelet amount of ADP and ATP. RESULTS: Platelet count, size and aggregation wholly recovered after BMT. The post-transplant content of platelet nucleotides was normal. CONCLUSIONS: Platelet function can be totally restored with cyclophosphamide/busulphan conditioned BMT in WAS. Platelet defects in this disease are due to defective thrombopoiesis.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Síndrome de Wiskott-Aldrich
/
Plaquetas
/
Busulfano
/
Trasplante de Médula Ósea
/
Purgación de la Médula Ósea
/
Ciclofosfamida
Límite:
Child, preschool
/
Humans
Idioma:
Es
Revista:
Sangre (Barc)
Año:
1993
Tipo del documento:
Article
Pais de publicación:
España