99mTc labeling white blood cells with a simple technique: clinical application.

Gutfilen, B; Pellini, M P; de Roure e Neder, J; de Amarante Júnior, J L; Evangelista, M G; Fernandes, S R; Bernardo-Filho, M

Gutfilen, B; Pellini, M P; de Roure e Neder, J; de Amarante Júnior, J L; Evangelista, M G; Fernandes, S R; Bernardo-Filho, M.

Afiliación

Gutfilen B; Departamento de Biofísica e Biometria, Universidade do Estado do Rio de Janeiro, Brasil.

Ann Nucl Med ; 8(1): 85-9, 1994 Feb.

Article en En | MEDLINE | ID: mdl-8204402

RESUMEN

Several radionuclides and different methods have been employed as cellular labels to study inflammatory sites in man. Here we present the results obtained with white blood cells (WBC) labeled with 99mTc using a simple and low cost new technique (SnTec). WBC were incubated with 12 micrograms/ml of stannous chloride for 10 min at room temperature. Then 99mTc was added. After 10 min, the 99mTc-labeled WBC were washed and injected into the patient. Comparison studies with 99mTc-labeled WBC using the HMPAO technique were carried out in patients with suspected osteomyelitis. Since the results are similar with both methods, we suggest the use of SnTec to label WBC, in cases of inflammatory diseases.

Asunto(s)

Marcaje Isotópico/métodos; Leucocitos; Osteomielitis/diagnóstico por imagen; Tecnecio; Adolescente; Adulto; Femenino; Humanos; Masculino; Persona de Mediana Edad; Compuestos de Organotecnecio; Oximas; Cintigrafía; Exametazima de Tecnecio Tc 99m

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteomielitis / Tecnecio / Marcaje Isotópico / Leucocitos Límite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Nucl Med Asunto de la revista: MEDICINA NUCLEAR Año: 1994 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Japón

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