Effects of H2 blockers and omeprazole on peptic secretion: a prospective, randomized study in duodenal ulcer subjects.
Acta Gastroenterol Belg
; 56(2): 223-8, 1993.
Article
en En
| MEDLINE
| ID: mdl-8103616
UNLABELLED: Aim of the present study has been to investigate the possible modifications of peptic secretion after a period with H2 blockers and omeprazole, evaluating in the same patient pepsinogen group A levels in gastric mucosa and pepsin in gastric juice. 54 active duodenal ulcer were studied: during an upper gastrointestinal endoscopy a sample of gastric juice and one fundus biopsy were taken before and after four weeks 300 mg/daily ranitidine (23 patients), 40 mg/daily famotidine (7 patients), 300 mg/daily nizatidine (12 patients) therapy and 40 mg/daily omeprazole (12 patients) therapy. RESULTS: H2-blockers and omeprazole treatment determines a non statistically significant decrease of pepsin in gastric juice and in pepsinogen group A in gastric mucosa.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Omeprazol
/
Pepsina A
/
Úlcera Duodenal
/
Antagonistas de los Receptores H2 de la Histamina
Tipo de estudio:
Clinical_trials
/
Observational_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
/
Newborn
Idioma:
En
Revista:
Acta Gastroenterol Belg
Año:
1993
Tipo del documento:
Article
Pais de publicación:
Bélgica