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Arterial thrombosis: a rare complication of the nephrotic syndrome.
Farkas, J C; Tabet, G; Marzelle, J; Cormier, F; Laurian, C; Cormier, J M.
Afiliación
  • Farkas JC; Department of Vascular Surgery, Hôpital Saint Joseph, Paris, France.
Cardiovasc Surg ; 1(3): 265-9, 1993 Jun.
Article en En | MEDLINE | ID: mdl-8076043
Arterial thrombosis is a rare complication of the nephrotic syndrome, occurring mainly in men. Two cases of arterial thrombosis are described, the first affecting a 54-year-old man in whom aortic thrombosis initiated the nephrotic syndrome and who relapsed 1 year later resulting in graft thrombosis, the second affecting a 15-year-old male patient with extensive popliteal and distal arterial thrombosis, followed by recurrent venous bypass thrombosis. A review of the literature shows that arterial thrombosis occurs primarily in the femoropopliteal, renal and coronary arteries. The genesis of arterial thrombosis in patients with nephrotic syndrome involves increased blood viscosity, platelet adhesion and aggregation, high levels of fibrinogen, low levels of serum antithrombin III, diuretic agents and steroid therapy. For high-risk patients with low levels of plasma albumin or those receiving steroids, anticoagulation therapy should be introduced to prevent thrombosis. Urine protein should be evaluated in patients with arterial thrombosis of unknown origin.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades de la Aorta / Arteria Poplítea / Trombosis / Nefrosis Lipoidea / Síndrome Nefrótico Límite: Adolescent / Humans / Male / Middle aged Idioma: En Revista: Cardiovasc Surg Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 1993 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades de la Aorta / Arteria Poplítea / Trombosis / Nefrosis Lipoidea / Síndrome Nefrótico Límite: Adolescent / Humans / Male / Middle aged Idioma: En Revista: Cardiovasc Surg Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 1993 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Reino Unido