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Risk factors for anemia in young children in rural Malawi.
Reed, S C; Wirima, J J; Steketee, R W.
Afiliación
  • Reed SC; Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Am J Trop Med Hyg ; 51(2): 170-4, 1994 Aug.
Article en En | MEDLINE | ID: mdl-8074250
Anemia is an increasingly recognized health problem in African children. To determine the prevalence of and risk factors for anemia in young children, we enrolled 252 pregnant women and studied their newborn infants in Mangochi District in southern Malawi. At the first follow-up visit after birth at approximately two months of age, the mean hematocrit value of the 252 infants was 29.5%, and 64 infants (25%) were anemic (hematocrit value < 25%). Placental malaria infection was the strongest risk factor for an infant having anemia at the first follow-up (relative risk = 2.0, P = 0.003). Infants who had Plasmodium falciparum parasitemia at the first follow-up had lower hematocrit values than infants without parasitemia (median 28% versus 31%; P = 0.02). Neither the mother's hematocrit at enrollment, her hematocrit at delivery, sex of the infant, nor fever illness in the infant was associated with having a hematocrit less than 25% at the first follow-up. Although infants with hematocrit values less than 25% were more likely than infants with higher hematocrit values to die during the first year of life, this difference was not statically significant (relative risk = 1.7, P = 0.15). In rural Malawi, anemia commonly affects young infants, is acquired early in life, and is probably a risk factor for death in infancy. Strategies to reduce anemia in infants must address P. falciparum infection, both during pregnancy and in the first few months of life.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Malaria Falciparum / Anemia Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Infant / Male / Newborn / Pregnancy País/Región como asunto: Africa Idioma: En Revista: Am J Trop Med Hyg Año: 1994 Tipo del documento: Article País de afiliación: Georgia Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Malaria Falciparum / Anemia Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Infant / Male / Newborn / Pregnancy País/Región como asunto: Africa Idioma: En Revista: Am J Trop Med Hyg Año: 1994 Tipo del documento: Article País de afiliación: Georgia Pais de publicación: Estados Unidos