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Olfactory memory in unmedicated schizophrenics.
Wu, J; Buchsbaum, M S; Moy, K; Denlea, N; Kesslak, P; Tseng, H; Plosnaj, D; Hetu, M; Potkin, S; Bracha, S.
Afiliación
  • Wu J; Department of Psychiatry, University of California, Irvine.
Schizophr Res ; 9(1): 41-7, 1993 Mar.
Article en En | MEDLINE | ID: mdl-8068050
Previous studies have indicated that schizophrenic patients have olfactory deficits. The question as to whether olfactory deficits are due to chronic effects of medication has not been addressed. This is the first paper to report that never-medicated schizophrenic patients also have olfactory deficits. Twenty four normal subjects and twenty unmedicated schizophrenic patients were examined with two tests of olfactory function: the University of Pennsylvania Smell Identification Test (UPSIT) and a match-to-sample olfactory memory test. Results indicated that schizophrenics did poorly on both the UPSIT and the olfactory match-to-sample memory test relative to sex and age-matched controls. ANCOVA showed that the deficit in performance on the olfactory match-to-sample test was still present even when the variance due to the UPSIT was taken out of the analysis. Deficits in olfactory identification and olfactory memory are consistent with the concept that schizophrenics have dysfunctional limbic systems.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Recuerdo Mental / Esquizofrenia / Psicología del Esquizofrénico / Olfato / Glucemia / Tomografía Computarizada de Emisión / Aprendizaje Discriminativo Límite: Humans Idioma: En Revista: Schizophr Res Asunto de la revista: PSIQUIATRIA Año: 1993 Tipo del documento: Article Pais de publicación: Países Bajos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Recuerdo Mental / Esquizofrenia / Psicología del Esquizofrénico / Olfato / Glucemia / Tomografía Computarizada de Emisión / Aprendizaje Discriminativo Límite: Humans Idioma: En Revista: Schizophr Res Asunto de la revista: PSIQUIATRIA Año: 1993 Tipo del documento: Article Pais de publicación: Países Bajos