Plasmid maintenance functions encoded on Dictyostelium discoideum nuclear plasmid Ddp1.
Mol Cell Biol
; 14(9): 6117-24, 1994 Sep.
Article
en En
| MEDLINE
| ID: mdl-8065344
All of the plasmid-carried genes expressed during vegetative growth are essential for long-term maintenance of plasmid Ddp1 in the nucleus of Dictyostelium discoideum. Deletion of Ddp1 genes expressed only during development had no detectable effect on plasmid maintenance. Deletion of vegetatively expressed genes, either singly or in pairs, resulted in (i) a rapid loss of plasmid from cells grown in the absence of selection for plasmid retention, (ii) variation in the proportion of monomer to multimer forms of the plasmid molecules, and/or (iii) abnormalities in plasmid copy number. At least two plasmid-encoded gene products influence patterns of expression of plasmid genes.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Plásmidos
/
Dictyostelium
Límite:
Animals
Idioma:
En
Revista:
Mol Cell Biol
Año:
1994
Tipo del documento:
Article
Pais de publicación:
Estados Unidos