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Effect of low and high amounts of a structured lipid containing fish oil on protein metabolism in enterally fed burned rats.
Selleck, K J; Wan, J M; Gollaher, C J; Babayan, V K; Bistrian, B R.
Afiliación
  • Selleck KJ; Laboratory of Nutrition/Infection, New England Deaconess Hospital, Harvard Medical School, Boston, MA 02215.
Am J Clin Nutr ; 60(2): 216-22, 1994 Aug.
Article en En | MEDLINE | ID: mdl-8030599
To determine the optimal fat intake and source in nutritional support, we measured the protein-sparing effects of a structured lipid (SL) derived from 60% medium-chain triglyceride (MCT) and 40% fish oil and a 50:50 soybean to safflower oil emulsion (long-chain triglyceride, LCT). Male Sprague-Dawley rats received an enteral diet for 7 d with either all nonprotein energy as dextrose (control diet) or 10% or 35% nonprotein energy as SL or LCT. The rats were burned on day 3. Indirect calorimetry and nitrogen balance were measured on day 2 (preburn) and days 4 and 6 (postburn). Respiratory quotient decreased postburn. There was a significant increase in total energy expenditure postburn, particularly with 35% LCT. Nitrogen balance was best without fat and 10% fat compared with 35% fat and with SL compared with LCT. These results confirm previous studies that fish oil-containing SLs possess protein-sparing effects in burn injury and that 10% SL seems optimal for nutritional support in burn injury.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quemaduras / Aceites de Pescado / Grasas de la Dieta / Proteínas / Nutrición Enteral Límite: Animals Idioma: En Revista: Am J Clin Nutr Año: 1994 Tipo del documento: Article Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quemaduras / Aceites de Pescado / Grasas de la Dieta / Proteínas / Nutrición Enteral Límite: Animals Idioma: En Revista: Am J Clin Nutr Año: 1994 Tipo del documento: Article Pais de publicación: Estados Unidos