[The role of pentoxifylline in acute lung injury complicated by pancreatitis].
Zhonghua Jie He He Hu Xi Za Zhi
; 17(2): 106-9, 128, 1994 Apr.
Article
en Zh
| MEDLINE
| ID: mdl-7994767
Caerulein-induced acute pancreatitis in rats commonly complicated ARDS-like acute lung injury. Acute pancreatitis induced by caerulein in the circulating neutrophil-depleted rat by hydroxyrea or with the administration of SOD, CAT or Pentoxifylline, the wet lung weight, lung capillary endothelial permeability decrease significantly compared to the caerulein group (P < 0.05). There are no lung morphologic evidences of neutrophil sequestration, interstial edema, intralveolar hemorrhage that seen in caerulein infusion animals. But it has no effect against the development of acute pancreatitis. It suggested that neutrophil and neutrophil-derived oxygen radical are the important mediators of acute lung injury complicated by pancreatitis.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Pancreatitis
/
Pentoxifilina
/
Síndrome de Dificultad Respiratoria
Límite:
Animals
Idioma:
Zh
Revista:
Zhonghua Jie He He Hu Xi Za Zhi
Año:
1994
Tipo del documento:
Article
Pais de publicación:
China