Susceptibility patterns and characterization of beta-lactamases in clinical isolates of Bacteroides fragilis.
Eur J Clin Microbiol Infect Dis
; 13(6): 475-80, 1994 Jun.
Article
en En
| MEDLINE
| ID: mdl-7957267
Strains of Bacteroides fragilis isolated from clinical specimens are known to be frequently resistant to penicillins or cephalosporins. The production of beta-lactamases is the major mechanism in this resistance. Up to now at least five types of beta-lactamase enzymes have been described in the Bacteroides fragilis group. The purpose of this study was to evaluate the susceptibility to different antibiotics and the prevalence of the beta-lactamase types among 100 Bacteroides fragilis strains isolated from clinical specimens in Italy. MICs of 11 antibiotics were determined by the reference agar dilution method and by the new E test (AB Biodisk, Sweden). Results showed an acceptable correlation between the MICs determined for most strains, although those obtained by the E test tended to be lower. In the beta-lactam resistant strains the enzyme activity and isoelectric points were determined on crude enzyme extract.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Bacteroides fragilis
/
Infecciones por Bacteroides
/
Beta-Lactamasas
/
Antibacterianos
Tipo de estudio:
Risk_factors_studies
Límite:
Humans
País/Región como asunto:
Europa
Idioma:
En
Revista:
Eur J Clin Microbiol Infect Dis
Asunto de la revista:
DOENCAS TRANSMISSIVEIS
/
MICROBIOLOGIA
Año:
1994
Tipo del documento:
Article
País de afiliación:
Italia
Pais de publicación:
Alemania