Endoscopic study of African AIDS patients with upper gastrointestinal symptoms.
East Afr Med J
; 71(8): 496-500, 1994 Aug.
Article
en En
| MEDLINE
| ID: mdl-7867539
ABSTRACT
PIP: 50-90% of people with AIDS experience disease of the upper gastrointestinal tract during the course of their illness, such as opportunistic infections, cytomegalovirus, Herpes simplex virus, and malignant neoplasms. This paper reports the endoscopic and histopathological findings among 100 AIDS patients in Mulago Hospital, Kampala, Uganda, who presented with upper gastrointestinal symptoms. The diagnosis of AIDS was based upon the World Health Organization clinical definition for AIDS. Observed morphological changes were biopsied, while duodenal contents were aspirated in each case for microscopic examination. Vomiting was reported among all patients, dysphagia and epigastric pain in 89%, odynophagia in 46%, retrosternal chest pain in 40%, haematemesis in 10%, and hiccough in 3%. Up to 74% of the patients had morphological changes in the esophagus, while 28% showed changes in the stomach. Only 15% demonstrated changes in the duodenum. Duodenal aspirate revealed giardia lamblia among 22%, acid fast bacilli in 7%, and cryptosporidium in 5%. Endoscopic findings were mostly observed in the esophagus. Candida was the main pathogen detected. Atrophic gastritis was also a recognizable finding among these patients.
Palabras clave
Acquired Immunodeficiency Syndrome; Africa; Africa South Of The Sahara; Biology; Demographic Factors; Developing Countries; Diseases; Eastern Africa; Endoscopy; English Speaking Africa; Examinations And Diagnoses; Gastrointestinal Effects; Histology; Hiv Infections; Physical Examinations And Diagnoses; Physiology; Population; Population Characteristics; Research Report; Signs And Symptoms; Uganda; Urban Population; Viral Diseases
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Endoscopía del Sistema Digestivo
/
Síndrome de Inmunodeficiencia Adquirida
/
Enfermedades Gastrointestinales
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Africa
Idioma:
En
Revista:
East Afr Med J
Año:
1994
Tipo del documento:
Article
País de afiliación:
Uganda
Pais de publicación:
Kenia