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Glucose 6-phosphate dehydrogenase from human erythrocytes: identification of N-acetyl-alanine at the N-terminus of the mature protein.
Camardella, L; Damonte, G; Carratore, V; Benatti, U; Tonetti, M; Moneti, G.
Afiliación
  • Camardella L; Institute of Protein Biochemistry and Enzymology, C.N.R., Napoli, Italy.
Biochem Biophys Res Commun ; 207(1): 331-8, 1995 Feb 06.
Article en En | MEDLINE | ID: mdl-7857286
Glucose 6-phosphate dehydrogenase from human erythrocytes has a blocked amino-terminus and no information could be obtained by direct sequencing of the intact protein. The peptide corresponding to the amino-terminal region was isolated from a tryptic digest of the whole protein and identified on the basis of its amino acid composition and of the failure to obtain Edman degradation. Determination of peptide mass by fast atom bombardment mass spectrometry allowed identification of the blocked amino-terminal residue as N-acetyl-alanine.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Alanina / Eritrocitos / Glucosafosfato Deshidrogenasa Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Biochem Biophys Res Commun Año: 1995 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Alanina / Eritrocitos / Glucosafosfato Deshidrogenasa Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Biochem Biophys Res Commun Año: 1995 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos