Substrate specificity of Epstein-Barr virus thymidine kinase.
Antimicrob Agents Chemother
; 38(9): 2175-9, 1994 Sep.
Article
en En
| MEDLINE
| ID: mdl-7811040
Purified recombinant protein encoded by the BXLF-I open reading frame of the Epstein-Barr virus genome has thymidine kinase activity. The substrate behaviors of various nucleosides toward this enzyme were tested. Halogenated deoxyuridines, zidovudine, and bromovinyldeoxyuridine are efficient substrates, while acyclovir and dihydroxypropylmethylguanine are relatively poor substrates for the Epstein-Barr virus thymidine kinase.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Timidina Quinasa
/
Herpesvirus Humano 4
Idioma:
En
Revista:
Antimicrob Agents Chemother
Año:
1994
Tipo del documento:
Article
Pais de publicación:
Estados Unidos