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Determination of kinetic rate and equilibrium binding constants for macromolecular interactions: a critique of the surface plasmon resonance literature.
O'Shannessy, D J.
Afiliación
  • O'Shannessy DJ; SmithKline Beecham Pharmaceuticals, King of Prussia.
Curr Opin Biotechnol ; 5(1): 65-71, 1994 Feb.
Article en En | MEDLINE | ID: mdl-7764646
Over the past year, the BIAcore system (which is based on the surface plasmon resonance phenomenon) has become increasingly popular for the study of macromolecular interactions. This biomolecular interaction analysis system allows the detection of macromolecular interactions in real time and in a label-free mode. The real-time detection properties of this technique suggest its potential in the generation of data relating to the kinetics of interaction of biomolecules.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sustancias Macromoleculares Idioma: En Revista: Curr Opin Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 1994 Tipo del documento: Article Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sustancias Macromoleculares Idioma: En Revista: Curr Opin Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 1994 Tipo del documento: Article Pais de publicación: Reino Unido