A method to collect, store and issue multiple aliquots of packed red blood cells for neonatal transfusions.
Vox Sang
; 68(2): 77-81, 1995.
Article
en En
| MEDLINE
| ID: mdl-7762225
Premature neonates require multiple red blood cell (RBC) transfusions. Single-donor programs have been proposed as a means to limit donor exposures, but methods must be developed to collect, store long-term and issue multiple aliquots of RBCs from a single donor. We evaluated a method by which RBCs could be collected, leukocyte depleted, repeatedly centrifuged for issuance as multiple small aliquots of high-hematocrit cells and then resuspended for continued storage throughout 42 days. The quality of RBCs handled by the method were compared to cells stored in standard fashion. Leakage of intracellular potassium, hemoglobin and lactic dehydrogenase into the extracellular fluid from RBCs processed by either method was comparable-indicating maintenance of RBC integrity. Multiple cultures, taken throughout the period of storage, were sterile to document that extensive handling did not introduce contamination. This new method appears promising as a means to provide RBCs for neonates.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Conservación de la Sangre
/
Recien Nacido Prematuro
/
Recolección de Muestras de Sangre
/
Transfusión de Eritrocitos
Límite:
Humans
/
Newborn
Idioma:
En
Revista:
Vox Sang
Año:
1995
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Reino Unido