Results of a randomized clinical trial comparing two radiation schedules in the palliative treatment of brain metastases.
Radiother Oncol
; 26(2): 111-6, 1993 Feb.
Article
en En
| MEDLINE
| ID: mdl-7681997
In 216 patients with brain metastases two schedules of brain irradiation were compared in a randomized trial: one course of 18 Gy/3 fractions/3 days versus the same fractionation followed by a second course of radiotherapy with a one-month time interval. The second course was identical to the first one or delivered 25 Gy/10 fractions/14 days. No difference in overall survival, nor in the neurologic response or in the incidence of complications was demonstrated. Two clinical factors appeared to be prognostic of the overall survival: the presence of multiple brain metastases and the presence of extracerebral metastases.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Cuidados Paliativos
/
Neoplasias Encefálicas
/
Irradiación Craneana
Tipo de estudio:
Clinical_trials
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Radiother Oncol
Año:
1993
Tipo del documento:
Article
País de afiliación:
Francia
Pais de publicación:
Irlanda