[A case of thymic carcinoma successfully controlled by combined chemotherapy and irradiation].
Nihon Kyobu Shikkan Gakkai Zasshi
; 33(6): 635-9, 1995 Jun.
Article
en Ja
| MEDLINE
| ID: mdl-7666619
There is no well established therapeutic protocol for advanced thymic carcinoma, although chemotherapy and irradiation can apparently be used to control the malignancy. Here we report a case of advanced thymic carcinoma successfully controlled by combination of treatment with systemic chemotherapy and irradiation. A 79-year-old man was admitted to the Hiratsuka Kyosai Hospital with complaints of productive cough and dyspnea. Chest roentgenogram and computerized tomography on admission revealed a tumorous lesion in the anterior mediastinum and on accumulation of left pleural and pericardial effusion fluid. The tumor was diagnosed as a thymic squamous cell carcinoma, after percutaneous needle biopsy. Because of extension to the left pleura and cardiac sac, the tumor was considered to be unresectable and systemic chemotherapy (CDDP + VDS + MMC) was begun. After drainage of the pericardial effusion fluid, intrapericardial injection of MMC was also done. The anterior mediastinum was irradiated. The patient has been doing well, with regression of the thymic tumor for 48 months after irradiation. This case provides important information that can be used to establish an effective therapeutic regimen for advanced thymic carcinoma.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias del Timo
/
Carcinoma de Células Escamosas
/
Protocolos de Quimioterapia Combinada Antineoplásica
Tipo de estudio:
Guideline
Límite:
Aged
/
Humans
/
Male
Idioma:
Ja
Revista:
Nihon Kyobu Shikkan Gakkai Zasshi
Año:
1995
Tipo del documento:
Article
Pais de publicación:
Japón