Visceral larva migrans in mice experimentally infected with Baylisascaris transfuga (Ascarididae: Nematoda).
Parassitologia
; 36(3): 321-9, 1994 Dec.
Article
en En
| MEDLINE
| ID: mdl-7638005
Laboratory bred albino mice, weighing 20 to 25 g, were orally infected with 2000 Baylisascaris transfuga infective eggs each. Mice were randomly chosen and sacrificed on days 1, 2, 3, 10, 15, 24 and 70 post-infection. Samples of intestine, mesenteric lymph nodes, liver, lungs, heart, spleen, kidneys, uterus, brain and skeletal muscles were collected and processed for conventional histopathology. In the early infection the major necropsy findings were focal haemorrhages on the intestinal wall, liver, lungs and brain. Histologically, larvae were found in haemorrhagic areas. In the subacute-chronic infection white nodules were scattered through all the examined organs, except the brain. Histologically, the white nodules corresponded to granulomas containing larvae surrounded by lymphocytes, eosinophil leukocytes and macrophages. The migration of B. transfuga larvae in spleen, kidneys and uterus of infected mice appears to have not been reported by previous workers. The possible role of B. transfuga larvae in the Visceral Larva Migrans syndrome is discussed.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ascaridoidea
/
Larva Migrans Visceral
/
Infecciones por Ascaridida
Límite:
Animals
País/Región como asunto:
Europa
Idioma:
En
Revista:
Parassitologia
Año:
1994
Tipo del documento:
Article
País de afiliación:
Italia
Pais de publicación:
Italia