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Continuous infusion etoposide/carboplatin for treatment of refractory acute leukemia.
Letendre, L; Noel, P; Tefferi, A; Solberg, L A; Gastineau, D A; Hoagland, H C.
Afiliación
  • Letendre L; Department of Internal Medicine, Mayo Foundation, Rochester, Minnesota 55905, USA.
Am J Clin Oncol ; 18(5): 382-4, 1995 Oct.
Article en En | MEDLINE | ID: mdl-7572751
Etoposide (125 mg/m2/d) and carboplatin (200 mg/m2/d) were administered by continuous 5-day intravenous infusion to 10 patients with relapsed or refractory acute leukemia (7 ANLL, 1 ALL, 2 blast crisis of CGL). No complete or partial response was observed despite dose-limiting toxicity characterized by severe diarrhea in four patients and neutropenic colitis in two additional cases. We cannot recommend the present schedule of drug administration for the treatment of acute leukemia.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia / Protocolos de Quimioterapia Combinada Antineoplásica / Terapia Recuperativa / Recurrencia Local de Neoplasia Límite: Adolescent / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Am J Clin Oncol Año: 1995 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Buscar en Google
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia / Protocolos de Quimioterapia Combinada Antineoplásica / Terapia Recuperativa / Recurrencia Local de Neoplasia Límite: Adolescent / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Am J Clin Oncol Año: 1995 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos