Sequence of the functional human keratin K14 promoter.
Gene
; 153(2): 297-8, 1995 Feb 14.
Article
en En
| MEDLINE
| ID: mdl-7533118
The K14 keratin is an intermediate filament produced in squamous epithelia. This tissue-specific expression is directed by the promoter (pK14) of the K14 gene which has been used extensively to direct the expression of transgenes to the skin. Human K14 was cloned and the upstream sequence is presented. In transient transfections, pK14 directs expression of a luciferase reporter in keratinocytes much more potently than in breast cancer cells.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Regulación de la Expresión Génica
/
Regiones Promotoras Genéticas
/
Queratinas
Límite:
Humans
Idioma:
En
Revista:
Gene
Año:
1995
Tipo del documento:
Article
Pais de publicación:
Países Bajos