[Chemoimmunotherapy of malignancies of the gastrointestinal tract]. / Chemoimmuntherapie bei Malignomen des Gastrointestinaltrakts.
Immun Infekt
; 22(2): 58-9, 1994 Apr.
Article
en De
| MEDLINE
| ID: mdl-7525456
Stimulation of the immune response could be obtained in outpatients with inoperable locally advanced or metastasizing gastrointestinal tumors (n = 56), who were palliatively treated with cyclophosphamide (cy), 350 mg/m2 i.v., thymostimulin, echinacin i.m. and in part additionally with epirubicin, 15 mg/m2 i.v. At present, outpatients with pancreatic (n = 7) or colon carcinomas (n = 1) receive interleukin 2 (IL-2) intralesionally, 2 x 10(5) Cetus units (CU), days 3, 5 and 7 after cy, and by portable continuous infusion systems i.v., 3 x 10(5) CU/day, days 3-8 after cy. Subsets of lymphocytes slightly decreased in the patients' peripheral blood, recall antigen reactivity slightly increased. Patients' mean survival time was 5.7 +/- 1.7 months.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Gastrointestinales
Límite:
Humans
Idioma:
De
Revista:
Immun Infekt
Año:
1994
Tipo del documento:
Article
Pais de publicación:
Alemania