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Tuberculosis presenting as immune thrombocytopenic purpura.
al-Majed, S A; al-Momen, A K; al-Kassimi, F A; al-Zeer, A; Kambal, A M; Baaqil, H.
Afiliación
  • al-Majed SA; College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Acta Haematol ; 94(3): 135-8, 1995.
Article en En | MEDLINE | ID: mdl-7502629
Various haematological abnormalities commonly occur in active tuberculosis (TB). However, thrombocytopenia is rare and immune thrombocytopenic purpura (ITP) is mentioned only in few case reports. We found that of 846 cases with active TB, 9 (1%) presented with ITP as the only abnormality. Three out of these 9 cases had disseminated miliary TB, 3 an abdominal abscess or lymphadenitis, and 3 pulmonary TB; none had palpable splenomegaly. All patients had purpura and the platelet count varied between 4 and 21 x 10(9)/l, and the bone marrow showed increased megakaryocytes. All tuberculous patients showed initially a poor platelet count response to steroid therapy. The platelet count returned to normal 2-6 weeks after oral prednisone combined with antituberculous drugs.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis / Púrpura Trombocitopénica Idiopática / Antituberculosos Tipo de estudio: Diagnostic_studies / Observational_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Acta Haematol Año: 1995 Tipo del documento: Article País de afiliación: Arabia Saudita Pais de publicación: Suiza
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis / Púrpura Trombocitopénica Idiopática / Antituberculosos Tipo de estudio: Diagnostic_studies / Observational_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Acta Haematol Año: 1995 Tipo del documento: Article País de afiliación: Arabia Saudita Pais de publicación: Suiza