Clostridium difficile colitis: recent therapeutical and immunological considerations.
Acta Gastroenterol Belg
; 58(3-4): 313-7, 1995.
Article
en En
| MEDLINE
| ID: mdl-7491844
Clostridium difficile is the main etiological agent of antibiotic associated diarrhoea and pseudomembranous colitis (PMC). It is considered as the most frequent agent of infectious diarrhoea occurring in hospitalized patients, in whom it is responsible for a high morbidity and occasional mortality even when the diagnosis and the treatment are pursued aggressively (1). The pathology is due to the production of at least two toxins: toxin A is an enterotoxin which induces intestinal tissue damage and a fluid response and toxin B is a cytotoxin which lacks any enterotoxic activity but is believed to exert an additive effect in vivo (2).
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Clostridioides difficile
/
Infecciones por Clostridium
/
Colitis
Límite:
Humans
Idioma:
En
Revista:
Acta Gastroenterol Belg
Año:
1995
Tipo del documento:
Article
País de afiliación:
Bélgica
Pais de publicación:
Bélgica