HlA antigens and steroid responsive nephrotic syndrome of childhood.

O'Regan, D; O'Callaghan, U; Dundon, S; Reen, D J

O'Regan, D; O'Callaghan, U; Dundon, S; Reen, D J.

Tissue Antigens ; 16(2): 147-51, 1980 Aug.

Article en En | MEDLINE | ID: mdl-7466782

RESUMEN

Fifty-four unrelated children with steroid responsive nephrotic syndrome of childhood were studied for 24 alleles at the HLA--A and B loci. A significantly increased incidence of HLA--B8 (Pc less than 0.01) was observed compared to controls. No association between response to cyclophosphamide therapy and HLA antigens was seen.

Asunto(s)

Corticoesteroides/uso terapéutico; Antígenos HLA/genética; Síndrome Nefrótico/inmunología; Niño; Preescolar; Ciclofosfamida/uso terapéutico; Haploidia; Humanos; Síndrome Nefrótico/tratamiento farmacológico; Síndrome Nefrótico/etiología

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Corticoesteroides / Antígenos HLA / Síndrome Nefrótico Tipo de estudio: Etiology_studies Límite: Child / Child, preschool / Humans Idioma: En Revista: Tissue Antigens Año: 1980 Tipo del documento: Article Pais de publicación: Reino Unido

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