Influence of sodium-independent gamma-aminobutyric acid binding on the assay of sodium-dependent gamma-aminobutyric acid binding in a membrane preparation of rat brain.
J Neurochem
; 36(1): 313-6, 1981 Jan.
Article
en En
| MEDLINE
| ID: mdl-7463057
A large amount of [3H]GABA was bound to crude synaptic membrane fractions of rat, by sodium-independent process in a medium that contained 100 microM [3H]GABA used for assaying GABA uptake site. This [3H]-GABA binding was different from receptor binding of GABA. It was confirmed that this sodium-independent [3H]GABA binding scarcely occurred in the presence of a physiological concentration of sodium chloride, and that sodium-independent GABA binding had a negligible influence on sodium-dependent GABA binding.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Membranas Sinápticas
/
Encéfalo
/
Cloruro de Sodio
/
Ácido gamma-Aminobutírico
Límite:
Animals
Idioma:
En
Revista:
J Neurochem
Año:
1981
Tipo del documento:
Article
Pais de publicación:
Reino Unido