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Effectiveness of triglycyl vasopressin in persistent hematuria associated with sickle cell hemoglobin.
Arch Intern Med ; 140(12): 1589-93, 1980 Dec.
Article en En | MEDLINE | ID: mdl-7458494
Two cases of persistent hematuria associated with the presence of sickle cell hemoglobin were treated intravenously with triglycyl vasopressin, a drug not previously used for this condition. One patient, a 16-year-old boy, had hemoglobin AS. Both patients had a history of severe hematuria persisting over several months, resistant to the usual forms of therapy, and requiring numerous transfusions. In each patient, the condition responded to intravenous triglycyl vasopression therapy, with cessation of hematuria. Experimental studies in dogs indicate that triglycyl vasopressin reduces renal blood flow substantially. Further trial of triglycyl vasopressin in severe hematuria associated with the presence of sickle cell hemoglobin appears to be indicated.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hemoglobina Falciforme / Lipresina / Hematuria / Anemia de Células Falciformes Tipo de estudio: Diagnostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Animals / Female / Humans / Male Idioma: En Revista: Arch Intern Med Año: 1980 Tipo del documento: Article Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hemoglobina Falciforme / Lipresina / Hematuria / Anemia de Células Falciformes Tipo de estudio: Diagnostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Animals / Female / Humans / Male Idioma: En Revista: Arch Intern Med Año: 1980 Tipo del documento: Article Pais de publicación: Estados Unidos