Alkaline phosphatase protein increases in response to prednisolone in HeLa cells.
Biochem J
; 200(2): 461-4, 1981 Nov 15.
Article
en En
| MEDLINE
| ID: mdl-7340849
Quantification of term-placental alkaline phosphatase isoenzyme protein in HeLa TCRC-1 cells grown in the presence and absence of prednisolone indicates that there is a net increase in amount of enzyme-specific protein in prednisolone-stimulated cells. In a similar analysis of HeLa D98AH2 cells, prednisolone treatment causes the appearance of term-placental alkaline phosphatase protein and the loss of the intestinal isoenzyme protein. These results support the interpretation that the response of these cells to corticosteroids is the net accumulation of alkaline phosphatase protein rather than the modification of pre-existing enzyme to a more active state.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Proteínas Gestacionales
/
Prednisolona
/
Fosfatasa Alcalina
/
Isoenzimas
Límite:
Humans
Idioma:
En
Revista:
Biochem J
Año:
1981
Tipo del documento:
Article
Pais de publicación:
Reino Unido