[1,6-Disubstituted 3-methylquinoxalin-2(1H)-ones. Effect on acquisition and modification of a conditioned avoidance response in the rat]. / 3-Metilchinossalin-2(1H)-oni 1,6-disostituiti. Effetto sull'acquisizione e sulla modificazione di una risposta condizionata di "avoidance" nel ratto.
Farmaco Sci
; 36(5): 359-71, 1981 May.
Article
en It
| MEDLINE
| ID: mdl-7238852
Sixteen derivatives of 3-methylquinoxalin-2(1H)-one were prepared; they are variously substituted on position 6 (R = H, COCH3, OCH3, CF3) and bear on position 1 an aminoalkyl chain (dimethylaminoethyl, dimethylaminopropyl, N-methylpiperazinylpropyl and morpholinylethyl). Most of these compounds exhibit a high degree of deconditioning activity on rats; compound (X) is significantly more active than chlorpromazine in the tests used.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Quinoxalinas
/
Reacción de Prevención
Límite:
Animals
Idioma:
It
Revista:
Farmaco Sci
Año:
1981
Tipo del documento:
Article
Pais de publicación:
Italia