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[Sites of synthesis of acetylcholine receptors in denervated muscles]. / Lieux de synthèse du recepteur pour l'acétylcholine dans les muscles dénérvés]
Bull Assoc Anat (Nancy) ; 64(186): 387-90, 1980 Sep.
Article en Fr | MEDLINE | ID: mdl-7214035
Muscle fibres binding with 125I alpha-bungarotoxine from Bungarus Multicinctus, after treatment with saponine, shows (in electron microscope autoradiography) intracellular binding sites identifying sites of acetylcholine receptor synthesis. In innervated muscle, the acetylcholine receptor is located only at the neuromuscular junction. In denervated muscle the receptor is distributed along the whole sarcolemma; in this situation the acetylcholine receptor is synthesized "ex novo" in the membrane system over the whole length of the muscle fibre.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores Colinérgicos / Músculos Límite: Animals Idioma: Fr Revista: Bull Assoc Anat (Nancy) Año: 1980 Tipo del documento: Article Pais de publicación: Francia
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores Colinérgicos / Músculos Límite: Animals Idioma: Fr Revista: Bull Assoc Anat (Nancy) Año: 1980 Tipo del documento: Article Pais de publicación: Francia