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[Severe intoxication after combined chemotherapy of a sigma-adenocarcinoma with peptichemio and 5-fluorouracil (author's transl)]. / Schwere Intoxikation nach kombinierter Chemotherapie eines Sigma-Adenokarzinoms mit Peptichemio und 5-Fluorouracil.
Wien Med Wochenschr ; 132(9): 201-4, 1982 May 15.
Article en De | MEDLINE | ID: mdl-7113229
After perioperative adjuvant chemotherapy of a sigma-adenocarcinoma with 400 mg peptichemio and 500 mg 5-fluorouracil a 61-year-old woman developed a severe intoxication: myelosuppression with pancytopenia, gastroenteritis and ulcerative proctitis, toxic hepato- and myocardiopathy, impaired renal function and alopecia. As a result of reduced resistance pneumonias, urinary tract infection, sepsis, cytomegaly infection and candidiasis of the oral mucosa occurred. The toxic effects are attributed mainly to the high dose of peptichemio.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Peptiquimio / Neoplasias del Colon Sigmoide / Adenocarcinoma / Fluorouracilo / Melfalán Límite: Female / Humans / Middle aged Idioma: De Revista: Wien Med Wochenschr Asunto de la revista: MEDICINA Año: 1982 Tipo del documento: Article Pais de publicación: Austria
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Peptiquimio / Neoplasias del Colon Sigmoide / Adenocarcinoma / Fluorouracilo / Melfalán Límite: Female / Humans / Middle aged Idioma: De Revista: Wien Med Wochenschr Asunto de la revista: MEDICINA Año: 1982 Tipo del documento: Article Pais de publicación: Austria