Immunologic studies of male infertility.
Fertil Steril
; 30(4): 426-9, 1978 Oct.
Article
en En
| MEDLINE
| ID: mdl-710614
Blood and semen samples were obtained from 13 men who had self-agglutination of spermatozoa and spermatozoal antibodies in their sera. The seminal plasma of these men produced spermatozoal immobilization and agglutination when added to normal semen from healthy men. Analysis of the seminal plasma samples showed that immunoglobulin G (IgG) levels were higher in the study group than in the control subjects. They contained IgA and complements C3 and C4, whereas only 2 of 15 samples from normal men contained IgA, and only one case contained C3 and C4. IgM was detected in 10 samples of the study group and in one sample of the control group. IgG levels in the blood of the study group were significantly higher than those in the blood of control subjects. Therefore, the immunoglobulins which probably play a role in the mechanism of autoagglutination and immobilization of spermatozoa are IgG, IgA, and IgM, and complements C3 and C4.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Semen
/
Proteínas del Sistema Complemento
/
Inmunoglobulinas
/
Infertilidad Masculina
Límite:
Humans
/
Male
Idioma:
En
Revista:
Fertil Steril
Año:
1978
Tipo del documento:
Article
Pais de publicación:
Estados Unidos