Blood pressure changes and cardiovascular lesions found in rats given T-2 toxin, a trichothecene secondary metabolite of certain Fusarium microfungi.
Toxicol Lett
; 10(1): 35-40, 1982 Jan.
Article
en En
| MEDLINE
| ID: mdl-7080066
White weanling rats were given intragastrically 4 doses of T-2 toxin (3 alpha-hydroxy-4 beta-1,5-diacetoxy-8 alpha-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene) a secondary metabolite of certain Fusarium species, 6 out of 9 treated rats developed increased blood pressure; these animals showed microscopically severe cardiovascular abnormalities. Occasional contamination of foodstuffs wh Fusarium may contribute to hypertension and cardiovascular lesions in animals and man.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Sesquiterpenos
/
Toxina T-2
/
Presión Sanguínea
/
Sistema Cardiovascular
Límite:
Animals
Idioma:
En
Revista:
Toxicol Lett
Año:
1982
Tipo del documento:
Article
Pais de publicación:
Países Bajos