[Comparison of carminomycin and rubomycin action on the dynamics of the immune response to the T-independent Vi-antigen of S. typhi]. / Sravnenie deistviia karminomitsina i rubomitsina na dinamiku T-nezavisimomu Vi-antigenu S. typhi.
Antibiotiki
; 25(2): 140-4, 1980 Feb.
Article
en Ru
| MEDLINE
| ID: mdl-6965576
The effect of carminomycin and rubomycin on the dynamics of the primary immune response to T-independent Vi-antigen of S. typhi was studied. Differences in the character of the antibiotic effect indicative of the high selective effect of carminomycin on the multiplying cells or precursors of the antibody forming plasmocytes were noted. It was found that the carminomycin inhibitory effect on synthesis of hemagglutinins to Vi-antigen was higher than that to sheep red blood cells. Carminomycin was shown to impair the formation of the immunological memory, while rubomycin did not suppress the development of the "memory cell" clone to T-independent antigen.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Salmonella typhi
/
Carubicina
/
Daunorrubicina
/
Reacciones Antígeno-Anticuerpo
/
Antígenos Bacterianos
/
Antígenos de Superficie
Límite:
Animals
Idioma:
Ru
Revista:
Antibiotiki
Año:
1980
Tipo del documento:
Article
Pais de publicación:
Rusia