Two modes of longe-range orientation of DNA bases realized upon compaction.
Nucleic Acids Res
; 9(3): 743-52, 1981 Feb 11.
Article
en En
| MEDLINE
| ID: mdl-6938929
Formation of compact particles from linear DNA-anthracycline complexes is accompanied by appearance of intense bands in the CD spectra in the region of absorption of DNA bases (UV-region) and in the region of absorption of anthracycline chromophores (visible region). The intense (positive or negative) bands in the region of anthracycline absorption demonstrate an ordered helical location of anthracycline molecules on the DNA template. This fact, in its turn, is related to formation of the DNA superstructure in PEG-containing water-salt solutions with a long-range orientation of nitrogen bases. Possible types of DNA superstructures and the relation between the local- and the long-range order of bases in the DNA superstructure are discussed.
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1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
ADN
Límite:
Animals
Idioma:
En
Revista:
Nucleic Acids Res
Año:
1981
Tipo del documento:
Article
Pais de publicación:
Reino Unido