Transient hypothyroidism following radioiodine therapy for thyrotoxicosis.
Br J Radiol
; 56(665): 309-13, 1983 May.
Article
en En
| MEDLINE
| ID: mdl-6850213
A prospective study of thyroid function including serial tracer radioisotope uptake measurements in 55 patients treated with 131I therapy is described. Five patients had an episode of transient hypothyroidism within eight months of treatment: in three of these patients this was due to impaired organification of iodide, with normal iodide trapping by the thyroid (as measured by a twenty minute 123I uptake) being preserved. In contrast, in all patients who developed permanent hypothyroidism, iodide trapping was markedly diminished and did not recover. It is suggested that hypothyroidism due to organification failure following 131I therapy is potentially short-lived; where hypothyroidism is associated with gross impairment of iodide trapping, recovery is unlikely. Early iodine uptake measurements may be of value in selecting those patients whose hypothyroidism is transient and who do not require permanent thyroid hormone replacement.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Hipertiroidismo
/
Hipotiroidismo
/
Radioisótopos de Yodo
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Br J Radiol
Año:
1983
Tipo del documento:
Article
Pais de publicación:
Reino Unido