Simultaneous determination of trace elements in serum by energy-dispersive x-ray fluorescence spectrometry.
Clin Chem
; 30(8): 1300-3, 1984 Aug.
Article
en En
| MEDLINE
| ID: mdl-6744575
Energy-dispersive x-ray fluorescence is applied in the analysis of human serum to determine the concentrations of several elements simultaneously with minimal manipulation of the sample. The analytical procedure has been developed with standard sera, and standardization, detection limits, and reproducibility have been established. A 50-microL sample of diluted serum, to which an internal standard has been added, is deposited on a thin (4-microns thick) polypropylene film and analyzed by x-ray fluorescence. We report the statistical distributions of the concentrations of Fe, Cu, Zn, and Br obtained in the population (103 samples) studied, and report detection limits for the other 22 elements studied. The simplicity of the method, the high throughput, and the possibility of automating the measurements make this procedure suitable for screening large numbers of sera.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Espectrometría por Rayos X
/
Oligoelementos
Límite:
Humans
Idioma:
En
Revista:
Clin Chem
Asunto de la revista:
QUIMICA CLINICA
Año:
1984
Tipo del documento:
Article
Pais de publicación:
Reino Unido