[Augmentation of NK activity in peripheral blood lymphocytes of cancer patients by intermittent GE-132 administration].
Gan To Kagaku Ryoho
; 11(6): 1303-6, 1984 Jun.
Article
en Ja
| MEDLINE
| ID: mdl-6732257
The natural killer (NK) activity of peripheral blood lymphocytes from 18 cancer patients was studied prior to and after multiple administration of organo-germanium compound (Ge-132). In successive oral administration of Ge-132 at a dose of 1000 mg/day for 10 days, NK-activity of patients was augmented at 3 days, but by 10 days, depression of NK activity was observed in all cases. In intermittent oral administration of Ge-132, however, more than half of the patients with augmented NK activity at day 3 maintained the high activity level at day 10. This result suggests the superiority of intermittent administration of Ge-132 for clinical use.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Compuestos Organometálicos
/
Neoplasias Gástricas
/
Células Asesinas Naturales
/
Neoplasias del Colon
/
Germanio
/
Neoplasias Pulmonares
Límite:
Humans
Idioma:
Ja
Revista:
Gan To Kagaku Ryoho
Año:
1984
Tipo del documento:
Article
Pais de publicación:
Japón