Polypeptide synthesis directed by bacteriophage phi W-14 and by mutants defective in DNA synthesis.
J Virol
; 50(2): 529-32, 1984 May.
Article
en En
| MEDLINE
| ID: mdl-6708173
The latent period of bacteriophage phi W-14 is approximately 65 min when the doubling time of its host, Pseudomonas acidovorans, is 85 min. Host protein synthesis is shut off relatively slowly, stopping approximately 25 min after infection. There are several phases of phage-specific polypeptide synthesis during the latent period: early polypeptides appear within 10 min after infection; middle polypeptides start to appear between 10 nd 30 min; late polypeptides appear after 30 min. The lengths of time for which individual polypeptides are synthesized vary widely. Several late polypeptides do not appear in the virion. DNA replication is not required for late gene expression. The hypermodified pyrimidine, alpha-putrescinylthymine, appears not to be required in both strands of the DNA duplex for transcription.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Péptidos
/
Pseudomonas
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Bacteriófagos
/
Proteínas Virales
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Replicación del ADN
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Mutación
Idioma:
En
Revista:
J Virol
Año:
1984
Tipo del documento:
Article
Pais de publicación:
Estados Unidos