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[Transketolase activity and thiamine diphosphate content in oncological patients]. / Aktivnost' transketolazy i uroven' tiamindifosfata u onkologicheskikh bol'nykh.
Vopr Med Khim ; 29(5): 100-3, 1983.
Article en Ru | MEDLINE | ID: mdl-6649520
In blood of patients with cancer of stomach and mammary gland total thiamin content was measured by means of fluorimetric procedure, thiamindiphosphate (TDP)--by an enzymatic method, activity of transketolase was estimated in presence or in absence of TDP. Concentration of total thiamin in blood of healthy persons was 7.65 +/- 0.40 micrograms/100 ml; thiamindiphosphate--5.06 micrograms/100 ml activity of transketolase was 11.59 +/- 0.23 mmol/l. The "TDP" -effect was altered from 4% to 12%. In blood of oncological patients the concentration of total thiamin was 4.47 +/- 0.35 micrograms/100 ml and that of thiamindiphosphate 3.09 +/- 0.27 micrograms/100 ml, i.e. they were decreased by 40%. The transketolase activity was decreased by 20% (9.40 +/- 0.37 mmol/l); the "TDP" -effect was altered from 5% to 42%.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Gástricas / Tiamina Pirofosfato / Transcetolasa / Neoplasias de la Mama Límite: Female / Humans Idioma: Ru Revista: Vopr Med Khim Año: 1983 Tipo del documento: Article Pais de publicación: Rusia
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Gástricas / Tiamina Pirofosfato / Transcetolasa / Neoplasias de la Mama Límite: Female / Humans Idioma: Ru Revista: Vopr Med Khim Año: 1983 Tipo del documento: Article Pais de publicación: Rusia