The effect of medial preoptic-anterior hypothalamic lesions on testosterone plasma levels and testosterone conversion in the hypothalamus of male rats.
Neurosci Lett
; 39(3): 261-5, 1983 Sep 09.
Article
en En
| MEDLINE
| ID: mdl-6633956
Male Wistar rats were submitted to bilateral high frequency lesions in the medial preoptic-anterior hypothalamic area or to sham procedure. The behavioral effect of the lesions was observed and plasma testosterone (T) and estradiol (E2) were measured by radioimmunoassay. In vitro metabolism of T was studied in the hypothalamus. Lesions produced a permanent deficit in male sexual behavior, an increase of plasma T and E2, and of hypothalamic T aromatization, and a decrease of T conversion to 5 alpha-dihydrotestosterone (DHT).
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Área Preóptica
/
Ratas
/
Testosterona
/
Hipotálamo Anterior
/
Hipotálamo
Límite:
Animals
Idioma:
En
Revista:
Neurosci Lett
Año:
1983
Tipo del documento:
Article
Pais de publicación:
Irlanda