Synthesis and biophysical studies of short oligodeoxynucleotides with novel modifications: a possible approach to the problem of mixed base oligodeoxynucleotide synthesis.
Nucleic Acids Res
; 12(19): 7435-53, 1984 Oct 11.
Article
en En
| MEDLINE
| ID: mdl-6548562
The syntheses of 1,2-dideoxy-D-ribofuranose and 1,2-dideoxy-1-phenyl-beta-D-ribofuranose are described. Oligodeoxynucleotides containing these analogues have been synthesised and hybridized to their complementary strands. Hypochromicity studies have shown that these duplices are less stable than either the totally complementary duplex or those containing A.C and G.T mismatches.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Oligodesoxirribonucleótidos
/
Oligonucleótidos
Idioma:
En
Revista:
Nucleic Acids Res
Año:
1984
Tipo del documento:
Article
Pais de publicación:
Reino Unido