Frequency of chromosome aberrations in bone marrow of monkeys and their F1 after aflatoxin B1 injection.
Exp Pathol
; 26(3): 163-9, 1984.
Article
en En
| MEDLINE
| ID: mdl-6440807
A mutagenic effect of aflatoxin B1 (AFB1) in somatic cells of primates is investigated. It is shown that AFB1 elevated the frequency of chromosome aberrations in the bone marrow of two species of monkeys: Macaca mulatta and Papio hamadryas. Beside chromosome aberrations, genome mutations were found in these experimental primates. AFB1-induced chromosome aberrations were constantly revealed during two years of study. Increase in the frequency of chromosome aberrations could be demonstrated in Macaca babies born from females that had received AFB1 at the final stage of pregnancy.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Médula Ósea
/
Carcinógenos
/
Aberraciones Cromosómicas
/
Aflatoxinas
Límite:
Animals
Idioma:
En
Revista:
Exp Pathol
Año:
1984
Tipo del documento:
Article
Pais de publicación:
Alemania